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Source: Gay Health News  Nov 17, 2019

Ejaculating Does Not Affect Testosterone Levels

Ejaculating Does Not Affect Testosterone Levels
Source: Gay Health News  Nov 17, 2019
Gay Health News received many enquiries from many body conscious gay men whio wanted to know if  ejaculating during sex would lead to drastic drops in their testosterone levels which would lead to  their bodies aging and sagging, hence we took to the task of during some research to dispel any wrong notions that could lead to them having miserable sex lives!

Ejaculation does not result in changes changes in testosterone levels but there are changes in the hormones prolactin  (an increase) and dopamine (temporary decrease) Although prolactin and dopamine are both involved with testosterone, they do not appear to influence testosterone levels acutely.
To understand the biochemical aspects of the male orgasm, we will first observe abstinence periods. (periods with no sex of any sort or ejaculation.)
Typically higher serum testosterone  levels are seen during abstinence (3 weeks in cited study).[1] Non-significant Luteinizing Hormone increases have also been noted.[1] The difference between abstinence and non-abstinence appears to be about 0.5ng/ml when averaged out.[1]
Though higher testosterone levels are seen with abstinence,[2] orgasm does not acutely affect testosterone levels in the blood.[1] Although there is not much evidence for the spike in testosterone during abstinence, there does not appear to be counter evidence at the moment; it is an understudied topic.
The male orgasm can cause a significant spike in prolactin levels (approximately 10 to 15ng/ml) immediately after and upwards to 10-20 minutes later, at which it starts to decline.[1][3] This spike is dependent on ejaculation, and does not occur under non-orgasmic arousal.[4] This spike may serve to suppress further sexual desires.[5][6]
Various bodily function and cardiovascular parameters, such as heart rate and catecholamine (adrenaline, noradrenaline) levels are increased during sex/masturbation and orgasm.[3] Some measure of increase is seen during arousal.[4]
Normally various markers, such as Vasopressin and Follicle-Stimulating Hormone (FSH) remain unchanged.[4]
Almost all biochemical markers do not differ significantly when comparing orgasm after abstinence and orgasm without abstinence.[1] Slight increases were seen in heart rate and catecholamine (adrenaline) levels, but may be due to self-reported higher arousal on average.
In conclusion, testosterone has minimal interactions with orgasm, but is seen as a positive regulator of sexual desire or libido alongside dopamine.[7][8] Agents that increase dopamine levels or act like dopamine can increase frequency of erections and subjective sexual arousal.[9][10] Prolactin is the opposite here, and is a negative regulator of sexual appetite.
Typically, the actual ejaculatory process and erection process is mediated by serotonin and Nitric Oxide, as well as various mechanical contractions in the pelvic and penile region.[7] Drugs or supplements that interfere with serotonin reuptake (such as SSRIs) can reduce the orgasm response, and may be useful in treating premature ejaculation.[11][12]Dopamine is reduced temporarily as prolactin rises, as the two can be seen as antagonistic of each other. Levels shortly normalize.[13] The post-orgasm 'orgasmic state' of euphoria is mediated by prolactin and mimicked by ecstasy.[14]
For gay men worried about how your sex life affects your testosterone levels and your body contours, rest assured ejaculation does not  impact your testosterone levels.
  1. a b c d e f Exton MS, et al. Endocrine response to masturbation-induced orgasm in healthy men following a 3-week sexual abstinenceWorld J Urol. (2001)
  2. ^ Jiang M, et al. A research on the relationship between ejaculation and serum testosterone level in menJ Zhejiang Univ Sci. (2003)
  3. a b Krüger T, et al. Neuroendocrine and cardiovascular response to sexual arousal and orgasm in menPsychoneuroendocrinology. (1998)
  4. a b c Krüger TH, et al. Specificity of the neuroendocrine response to orgasm during sexual arousal in menJ Endocrinol. (2003)
  5. ^ Krüger TH, et al. Effects of acute prolactin manipulation on sexual drive and function in malesJ Endocrinol. (2003)
  6. ^ Krüger TH, et al. Orgasm-induced prolactin secretion: feedback control of sexual driveNeurosci Biobehav Rev. (2002)
  7. a b Stahl SM. The psychopharmacology of sex, Part 1: Neurotransmitters and the 3 phases of the human sexual responseJ Clin Psychiatry. (2001)
  8. ^ Motofei IG, Rowland DL. Neurophysiology of the ejaculatory process: developing perspectivesBJU Int. (2005)
  9. ^ Pharmacotherapy for Premature Ejaculation.
  10. ^ Assessment of erectogenic properties of apomorphine and yohimbine in man.
  11. ^ McMahon CG. Treatment of premature ejaculation with sertraline hydrochloride: a single-blind placebo controlled crossover studyJ Urol. (1998)
  12. ^ McMahon CG, Samali R. Pharmacological treatment of premature ejaculationCurr Opin Urol. (1999)
  13. ^ Krüger TH, Hartmann U, Schedlowski M. Prolactinergic and dopaminergic mechanisms underlying sexual arousal and orgasm in humansWorld J Urol. (2005)
  14. ^ Passie T, et al. Ecstasy (MDMA) mimics the post-orgasmic state: impairment of sexual drive and function during acute MDMA-effects may be due to increased prolactin secretionMed Hypotheses. (2005)